Search on: SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS 
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Descriptor English:   Serotonin Plasma Membrane Transport Proteins 
Descriptor Spanish:   Proteínas de Transporte de Serotonina en la Membrana Plasmática 
Descriptor Portuguese:   Proteínas da Membrana Plasmática de Transporte de Serotonina 
Synonyms English:   Neurotransmitter Transport Proteins, Serotonin-Specific
Neurotransmitter Transporters, Serotonin-Specific
Serotonin Plasma Membrane Transporter Proteins  
Tree Number:   D12.776.157.530.450.625.311
D12.776.157.530.562.374.875
D12.776.543.585.450.625.374
D12.776.543.585.562.374.875
Definition English:   Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SEROTONIN UPTAKE INHIBITORS. 
Entry Combination - descr/qualif English:   Serotonin Plasma Membrane Transport Proteins/antagonists & inhibitors use Serotonin Uptake Inhibitors
 
See Related English:   Receptors, Serotonin
 
History Note English:   2006(1992) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50907 
Unique Identifier:   D050486 

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